The Royal Parade service lane near Grattan Street will be closed to traffic—including bikes—for about four weeks from Friday 8 November.
The closures are around worksites on the western (outbound) side of Royal Parade near the Peter MacCallum Cancer Centre and Royal Melbourne Hospital.
Works involve relocation services to enable two entrances to be constructed for the new Metro Tunnel underground station in Grattan Street.
Bike riders will be diverted into the Royal Parade northbound centre lane at the Grattan Street intersection.
On weekdays, westbound rider access into Grattan Street will be via the Elizabeth Street northbound service lane and on weekends eastbound rider access on Grattan Street will be maintained and westbound cyclist access to Grattan Street will be via Flemington Road.
There will be lane closures in place on Elizabeth Street, Peel Street and Haymarket Roundabout to assist with safe merging during these works.
Access to hospitals, including for emergency services, and to local businesses will be maintained at all times.
Temporary fencing, signage and traffic controllers will be in place around the work sites.