I've tried Sayers Road, Old Geelong Road, Cherry Lane and Dohertys Road. To continue to the city I was planning to use Grieve Parade, Princess Highway, Barkly St, Dynon Rd...... Heavy traffic at some parts, lots of trucks.
Other option would be going south through Forsyth Rd, path along Skeleton Creek, Pt. Cook Rd, Central Ave. Queen St., Millers Road, ..... Heavy traffic too but scenery is nicer, few trucks.
Safest would be the proposed Federation Trail, if/when it comesinto service. What routes have you tried?
"Where ever you go, there you are."